- Category
- Science
- Published
- Thursday, July 16, 2026 at 12:49 AM
- Publisher
-
ScienceDaily
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Common constipation drug may help clear depression brain fog
Quick Summary
An existing constipation drug may have an unexpected new use: helping clear the "brain fog" that often lingers after depression. In a small clinical trial, people with a history of depression who took the medication prucalopride for about a week performed better on tests of memory, attention, and thinking speed than those who received a placebo. The drug targets a serotonin receptor found in both the gut and the brain, and researchers saw no significant side effects.
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